Lymphatic System Vocabulary Worksheet

Press Print worksheet to match twelve lymphatic system terms, lymph node, spleen and thymus among them, to their meanings.

A sample is on the sheet. What you type replaces it.

What you type stays in your browser. Nothing is sent to us.

NameDateMade at homeroomtools.comDraw a line from each one on the left to its partner on the right.Lymphatic system vocabularylymphatic systemlymphlymph nodelymphatic vesselspleenthymustonsilsbone marrowlymphocytetissue fluidhematopoiesisimmune responseclumps of tissue that guard thethroat's entrancethe bone filling in which everyblood cell beginsthe body's fight against a germ ithas detectedthe fluid filling the gaps betweenbody cellsthe network of lymph vessels,nodes and organsan organ by the stomach thatstrains the bloodfluid on its way from the tissuesback to the bloodthe body's nonstop production ofnew blood cellsa two-lobed chest organ that islargest in childrena thin-walled tube that carrieslympha small bean-shaped filter forlymphthe white blood cell type thatpacks the lymph nodes
NameDateMade at homeroomtools.comDraw a line from each one on the left to its partner on the right.Lymphatic system vocabularyAnswer keylymphatic systemlymphlymph nodelymphatic vesselspleenthymustonsilsbone marrowlymphocytetissue fluidhematopoiesisimmune responseclumps of tissue that guard thethroat's entrancethe bone filling in which everyblood cell beginsthe body's fight against a germ ithas detectedthe fluid filling the gaps betweenbody cellsthe network of lymph vessels,nodes and organsan organ by the stomach thatstrains the bloodfluid on its way from the tissuesback to the bloodthe body's nonstop production ofnew blood cellsa two-lobed chest organ that islargest in childrena thin-walled tube that carrieslympha small bean-shaped filter forlymphthe white blood cell type thatpacks the lymph nodes
More options

All 36 terms

Lymph, nodes and organs 12

  • bone marrow The bone filling in which every blood cell begins. There are two kinds. Red marrow is the working kind, and yellow marrow is mostly fat.
  • hematopoiesis The body's nonstop production of new blood cells. All three kinds of blood cell, red cells, white cells and platelets, grow from stem cells in the red marrow.
  • immune response The body's fight against a germ it has detected. During one, lymphocytes multiply in the lymphatic organs and travel in the blood to where they are needed.
  • lymph Fluid on its way from the tissues back to the blood. It is clear and watery. Lymph coming from the small intestine is milky with fat and is called chyle.
  • lymph node A small bean-shaped filter for lymph. Lymph enters through several vessels, trickles through the spaces inside and leaves by another vessel at a dent in one side.
  • lymphatic system The network of lymph vessels, nodes and organs. It has three jobs: it returns leaked fluid to the blood, takes up fats from food and defends the body.
Show all 36 terms (30 more)

Lymph, nodes and organs, continued

  • lymphatic vessel A thin-walled tube that carries lymph. Lymph moves through it in one direction only, out of the tissues. Small vessels merge into larger ones.
  • lymphocyte The white blood cell type that packs the lymph nodes. Its large, dark nucleus nearly fills the cell. Its two main types are the T cell and the B cell.
  • spleen An organ by the stomach that strains the blood. It is the largest lymphatic organ. It works on blood much as a lymph node works on lymph, and it holds a reserve of blood.
  • thymus A two-lobed chest organ that is largest in children. It lies behind the breastbone. In older adults the thymus is quite small.
  • tissue fluid The fluid filling the gaps between body cells. Its other name is interstitial fluid. It brings oxygen and nutrients to the cells, and once it enters a lymph capillary it is called lymph.
  • tonsils Clumps of tissue that guard the throat's entrance. The best-known pair is the palatine tonsils, at the back of the mouth. The one behind the nose is the adenoid.

Lymph, blood and flow 12

  • backflow Movement of a fluid in the wrong direction. The stretch of vessel between two valves is called a lymphangion. It tightens to pass lymph forward.
  • blood capillary A hair-thin blood vessel with a leaky wall. Fluid seeps out of it into the tissues, and most of that fluid goes straight back in. The lymphatic system collects the rest.
  • circulation The endless looping journey of blood in the body. Blood travels in a closed loop. Lymph travels one way and joins the loop near the heart.
  • lymph capillary A microscopic blind-ended tube where lymph begins. The cells of its wall overlap like tiny doors, so fluid can get in but not back out.
  • lymph heart An organ that pumps lymph in frogs and reptiles. Mammals have none. In people the lymphatic vessels themselves tighten to push lymph along.
  • plasma protein A protein dissolved in the liquid part of blood. Albumin is the most plentiful. Small proteins that leak out of the blood are carried back to it by lymph.
  • reabsorb To soak a fluid back up after letting it out. Of about 20 liters of fluid filtered out of the blood each day, roughly 17 are reabsorbed. The other 3 liters go home by way of the lymph.
  • red blood cell The oxygen-carrying cell that the spleen recycles. The spleen takes old and damaged ones out of the blood and saves their iron.
  • small intestine The gut section where lymph vessels take up fats. Its lining is covered with tiny fingers called villi. A lymph capillary in each one, a lacteal, takes in fats and the vitamins that dissolve in fat.
  • smooth muscle Involuntary muscle that squeezes a vessel narrower. Its squeezing is one of three things that move lymph. The others are the working of the skeletal muscles and the motion of breathing.
  • thoracic duct The body's main lymph channel, running up the chest. It drains every part of the body except the upper right quarter. It empties into the blood where two large veins meet, at the base of the neck on the left.
  • valve A pair of flaps that keeps fluid from slipping back. Lymphatic vessels have valves along their length, as veins do.

Tissues and cells of defense 12

  • antibody A Y-shaped protein that grips one kind of invader. Its other name is immunoglobulin. Each antibody fits a single target, as a key fits a lock.
  • antigen-presenting cell A cell that displays bits of an invader to T cells. Dendritic cells, macrophages and B cells can all do the job. Its short name is APC.
  • B cell A lymphocyte that matures in the bone marrow. Its B first stood for the bursa of Fabricius, the organ where these cells mature in birds. An activated B cell can become a plasma cell.
  • cell-mediated immunity Defense by cells directly, with no antibodies. Its T cells destroy body cells that a virus has already entered.
  • humoral immunity Defense carried by antibodies in the body's fluids. Humor is an old word for a body fluid. This is the branch of defense that B cells and plasma cells run.
  • lobule A small compartment inside an organ. Walls of connective tissue divide the spleen into lobules. Each lobe of the thymus is divided into them too.
  • lymphoid organ An organ where lymphocytes are made or put to work. The bone marrow and the thymus are primary lymphoid organs. Lymph nodes, the spleen and the tonsils are secondary ones.
  • MALT Lymphoid tissue under the linings of gut and airways. The letters stand for mucosa-associated lymphoid tissue. It makes up about half of the lymphoid tissue in the body.
  • plasma cell A cell that pours out one kind of antibody. One plasma cell can release several thousand antibodies a second.
  • T cell A white blood cell whose T stands for thymus. T cells begin in the bone marrow and move to the thymus to mature.
  • thymic involution The thymus growing smaller as the years go by. Fat slowly takes the place of the working tissue. It happens in almost all animals with a backbone.
  • trabecula A tiny beam of tissue that braces an organ inside. The word is Latin for small beam. Trabeculae reach inward from the outer coat of a lymph node and of the spleen.

How this list was compiled: Term list chosen for this site on 2026-10-13. Each meaning is written in our own words and was checked that day against the Dictionary of Cancer Terms of the National Cancer Institute (https://www.cancer.gov/publications/dictionaries/cancer-terms), entries lymphatic system, lymph, lymph node, lymph vessel, spleen, thymus, tonsil, bone marrow, lymphocyte, T cell, B cell, plasma cell, antibody, immune response, lymphoid, interstitial fluid, capillary, small intestine, red blood cell and antigen-presenting cell; against the Lymphatic System pages of the SEER Training Modules of the National Cancer Institute (https://training.seer.cancer.gov/anatomy/lymphatic/): Introduction to the Lymphatic System, Components of the Lymphatic System, Lymph Nodes, Tonsils, Spleen, Thymus and Review; and against articles of the English Wikipedia (https://en.wikipedia.org/), whose text is under the Creative Commons Attribution-ShareAlike license: Lymphatic system, Lymph, Lymph node, Lymphatic vessel, Spleen, Thymus, Tonsil, Bone marrow, Lymphocyte, T cell, B cell, Antibody, Plasma cell, Thoracic duct, Plasma protein, Lymph heart, Mucosa-associated lymphoid tissue, Thymic involution, Antigen-presenting cell, Humoral immunity, Cell-mediated immunity and Trabecula. Valve, reabsorb, backflow, circulation, lobule, smooth muscle and humoral rest on their entries in Wiktionary, the free dictionary (https://en.wiktionary.org/). The fact after each meaning is from the same pages. The list names parts of the body and what they do: it is a study aid for a science class, not health advice. Licence: own work

How it works

This lymphatic system vocabulary worksheet lists lymph, lymph node, lymphatic vessel, spleen, thymus, tonsils, bone marrow, lymphocyte and four more terms beside their meanings in mixed order. The key prints last. It is a study aid, with no diagram.

Read the full guide

Lymph, blood and flow

Set opens on Lymph, nodes and organs. The second set has lymph capillary, valve, thoracic duct, blood capillary, plasma protein, smooth muscle, small intestine, lymph heart, reabsorb, backflow, red blood cell and circulation.

Tissues and cells of defense

The third set has T cell, B cell, antibody, plasma cell, lymphoid organ, MALT, thymic involution, antigen-presenting cell, humoral immunity, cell-mediated immunity, lobule and trabecula.

  • Lacteal, chyle, adenoid, macrophage and antigen are answers on the lymphatic system crossword, not terms here.

Questions and answers

Is the lymphatic system part of the immune system or the circulatory system?

It belongs to the immune system and works alongside the circulatory system. Its organs and lymphocytes defend the body, and its vessels hand leaked fluid back to the blood.

What is lymph made of?

A clear, watery fluid much like the blood plasma it comes from. It carries proteins, fats, debris from the cells and white blood cells, lymphocytes among them.

How many lymph nodes are in the human body?

Hundreds: about 450 in an adult by one count. They sit along the lymphatic vessels throughout the body and cluster in the neck, the armpits, the chest, the abdomen and the groin.

What is the difference between T cells and B cells?

B cells make antibodies, and T cells do not. Some T cells destroy body cells that are infected, and helper T cells direct other defenders. Both kinds are lymphocytes that start out in the bone marrow.